C8476
Sigma
Combinatorial Chemistry: A Practical Approach
| ISBN-10: | 0-19-963754-7 |
| ISBN-13: | 978-0-19-963754-6 |
Description
| General description | Being a powerful modern technology, combinatorial chemistry has had implications in many areas of chemistry and biology, and the current approaches to drug, catalyst, receptor, and materials development and discovery are all included in this volume. It contains protocols on solid, liquid, and solution phase synthesis and expedient methods of library screening and evaluation, and explains the use of automation and robotics. |
Properties
| publication info | H. Fenniri, ed., Oxford University Press, 2000, 432 pp., soft cover |
Table Of Contents
| Table of Contents | Synthesis of combinatorial libraries using the portioning-mixing procedure One-bead-one-compound combinatorial library method Synthesis and screening of positional scanning synthetic combinatorial libraries High throughput combinatorial synthesis of discrete compounds in multimilligram quantities Positionally addressable parallel synthesis on membrane supports Resins and anchors for solid phase organic synthesis Organic reactions on solid support - an overview Analytical methods in combinatorial chemistry Multi-component reactions (mcrs) of isocyanides and their chemical libraries Multi-step solution phase combinatorial synthesis Experimental techniques in fluorous synthesis Dendrimer-supported combinatorial chemistry Automated solution phase synthesis and its application in combinatorial chemistry Combinatorial discovery and optimization of electrocatalysts Combinatorial library synthesis using polymer-supported catalysts Combinatorial Approaches to chiral catalysts discovery |






